SCHEMBL9306680

SCHEMBL9306680

C[Si]1(c2ccccc2)CC=CC1

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1484049 0.78 TSHR (0.33) LMNATSHRALOX12ACHE
SCHEMBL15637037 0.78 TSHR (0.33) LMNATSHRALOX12ACHE
SCHEMBL6440299 0.74 APOBEC3A (0.31) LMNATSHRALOX12ACHE
SCHEMBL9404264 0.74 LMNA (0.30) LMNATSHRALOX12ACHE
SCHEMBL17885704 0.74 APOBEC3A (0.31) LMNATSHRALOX12ACHE
SCHEMBL9303868 0.72 MAPT (0.32)
SCHEMBL9638266 0.72 TSHR (0.32) TSHR
SCHEMBL17885703 0.72 CYP2B6 (0.30)
Ammonia Solution, Strong SCHEMBL27725623 0.70
SCHEMBL1159877 0.69 HTR2C (0.36) LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300605-A Cross-linkable poly(unsaturated carbosilane) homopolymers and copolymers and method of making same UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1994-04-05 US disclosed
US-5260377-A Crosslinkable carbosilane polymer formulations UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1993-11-09 US disclosed
WO-1993017063-A1 CROSSLINKABLE CARBOSILANE POLYMER FORMULATIONS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1993-09-02 WO disclosed
US-5171810-A CROSSLINKABLE POLY(UNSATURATED CARBOSILANE) COPOLYMERS AND METHODS OF MAKING SAME UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1992-12-15 US disclosed
US-5171792-A Crosslinkable saturated and unsaturated carbosilane polymers and formulations UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1992-12-15 US disclosed
US-5169916-A Crosslinkable poly(unsaturated carbosilane) polymers and methods of making same UNIVERSITY OF SOUTH CALIFORNIA (US) 1992-12-08 US disclosed
US-5130390-A Crosslinkable saturated and unsaturated carbosilane polymers and formulations UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1992-07-14 US disclosed