Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.79 |
| ▸ | RPS6KA2 | Q15349 | 8/20 | 0.65 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.54 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | PTPRF | P10586 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | CDC25A | P30304 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304609 | 0.80 | RPS6KA2 (0.77) | ALOX5RPS6KA2RPS6KA3MEN1KMT2A | |
| SCHEMBL9303245 | 0.80 | ALOX5 (0.62) | ALOX5RPS6KA2MAPTMEN1KMT2A | |
| SCHEMBL11617992 | 0.78 | RPS6KA2 (1.00) | ALOX5RPS6KA2RPS6KA3BCHECES1 | |
| SCHEMBL4959962 | 0.77 | ALDH1A1 (0.50) | ALOX5RPS6KA2SCN2AMAPTMEN1 | |
| SCHEMBL9305057 | 0.76 | MEN1 (0.62) | ALOX5SCN2AMAPTMEN1KMT2A | |
| SCHEMBL1832812 | 0.76 | CA12 (0.60) | SCN2AMAPT | |
| SCHEMBL17550101 | 0.74 | CA1 (0.62) | SCN2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL29531485 | 0.74 | CA1 (0.62) | SCN2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL7821430 | 0.74 | RPS6KA2 (0.69) | RPS6KA2SCN2ARPS6KA3MEN1KMT2A | |
| SCHEMBL1061766 | 0.74 | RPS6KA2 (0.73) | RPS6KA2RPS6KA3BCHECES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546113-A1 | NONLINEAR OPTICAL MATERIALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-16 | — | — | EP | claimed |
| US-5312565-A | Nonlinear optical materials | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
| EP-0546113-A1 | NONLINEAR OPTICAL MATERIALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1992003417-A2 | NONLINEAR OPTICAL MATERIALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-05 | — | — | WO | disclosed |