Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA2 | Q15349 | 7/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 3/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11617992 | 0.85 | RPS6KA2 (1.00) | RPS6KA2KDM4ELMNARPS6KA3MAPK1 | |
| SCHEMBL7821430 | 0.85 | RPS6KA2 (0.69) | RPS6KA2RPS6KA3MAPK1HSD17B10CES1 | |
| SCHEMBL1061766 | 0.85 | RPS6KA2 (0.73) | RPS6KA2KDM4ELMNARPS6KA3MAPK1 | |
| SCHEMBL11887630 | 0.81 | MAPK1 (0.74) | RPS6KA2MAPK1HSD17B10MEN1KMT2A | |
| SCHEMBL16087635 | 0.81 | RPS6KA2 (0.56) | RPS6KA2MEN1KMT2A | |
| SCHEMBL9304040 | 0.80 | ALOX5 (0.79) | RPS6KA2RPS6KA3CES1BCHEMEN1 | |
| SCHEMBL12310042 | 0.78 | RPS6KA2 (0.65) | RPS6KA2KDM4ELMNARPS6KA3TDP1 | |
| SCHEMBL9305864 | 0.78 | KDM4E (0.56) | RPS6KA2KDM4ELMNAMAPK1TP53 | |
| SCHEMBL1296639 | 0.75 | ACHE (0.64) | TDP1MEN1KMT2A | |
| SCHEMBL30501207 | 0.75 | RPS6KA2 (0.59) | RPS6KA2KDM4EMAPK1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312565-A | Nonlinear optical materials | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1994-05-17 | — | — | US | disclosed |