Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.43 |
| ▸ | CA1 | P00915 | 9/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GGH | Q92820 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304979 | 0.78 | CA1 (0.46) | CA2CA1CA12CA9GAA | |
| SCHEMBL7282302 | 0.74 | GAA (0.59) | MMP9MMP8MMP13ADAMTS4GGH | |
| SCHEMBL9303840 | 0.73 | MMP9 (0.57) | MMP9MMP8MMP13ADAMTS4GGH | |
| SCHEMBL9304277 | 0.71 | MAPT (0.48) | GGHFOLH1GAATDP1 | |
| SCHEMBL9304269 | 0.71 | MAPT (0.48) | GGHFOLH1GAATDP1 | |
| SCHEMBL9516778 | 0.70 | CA2 (0.46) | CA2CA1GAA | |
| SCHEMBL28975397 | 0.69 | CA2 (0.52) | CA2CA1MMP9MMP8MMP13 | |
| SCHEMBL9520371 | 0.69 | CA2 (0.45) | CA2CA1GAA | |
| SCHEMBL28726877 | 0.68 | CA2 (0.41) | CA2CA1MMP9MMP8MMP13 | |
| SCHEMBL9303979 | 0.66 | CA2 (0.50) | CA2CA1CA12CA9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312565-A | Nonlinear optical materials | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1994-05-17 | — | — | US | disclosed |