Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 13/20 | 0.46 |
| ▸ | CA2 | P00918 | 13/20 | 0.46 |
| ▸ | CA4 | P22748 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516778 | 0.89 | CA2 (0.46) | CA1CA2CA4LMNAGAA | |
| SCHEMBL9520371 | 0.85 | CA2 (0.45) | CA1CA2CA4LMNAGAA | |
| SCHEMBL9304085 | 0.78 | CA2 (0.43) | CA1CA2CA12CA9GAA | |
| SCHEMBL491040 | 0.70 | ALOX5 (0.70) | LMNAGAACYP1A1L3MBTL1ALOX5 | |
| SCHEMBL9303979 | 0.70 | CA2 (0.50) | CA1CA2CA4CA12CA9 | |
| SCHEMBL27183087 | 0.68 | MAPT (0.67) | LMNAGAASMN1; SMN2 | |
| SCHEMBL776908 | 0.67 | HTR6 (0.42) | CA1CA2CA4CA12CA9 | |
| SCHEMBL8849931 | 0.65 | HSD11B1 (0.43) | CA1CA2 | |
| SCHEMBL15615854 | 0.64 | ALDH1A1 (0.58) | CA1CA2CA12CA9LMNA | |
| SCHEMBL9694727 | 0.64 | CA1 (0.37) | CA1CA2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312565-A | Nonlinear optical materials | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
| EP-0546113-A1 | NONLINEAR OPTICAL MATERIALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1992003417-A2 | NONLINEAR OPTICAL MATERIALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-05 | — | — | WO | disclosed |