Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3230225 | 0.80 | F2 (0.32) | F2LMNA | |
| SCHEMBL947216 | 0.77 | KMT2A (0.48) | F2LMNA | |
| SCHEMBL11082436 | 0.72 | CES2 (0.42) | F2LMNA | |
| SCHEMBL10503149 | 0.70 | NFE2L2 (0.46) | F2LMNA | |
| SCHEMBL11403405 | 0.70 | NFE2L2 (0.34) | F2LMNA | |
| SCHEMBL1851997 | 0.69 | KMT2A (0.37) | LMNA | |
| SCHEMBL6663799 | 0.68 | PTGS2 (0.30) | — | |
| SCHEMBL1193666 | 0.68 | CES1 (0.47) | F2LMNA | |
| SCHEMBL11546766 | 0.68 | ESR1 (0.40) | — | |
| SCHEMBL3012123 | 0.67 | CYP1B1 (0.56) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5376669-A | Antitumor agents | CIBA-GEIGY CORP. (US) | 1994-12-27 | — | — | US | disclosed |