Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 5/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9452733 | 0.90 | BRS3 (0.56) | BRS3AGTR1AGTR2 | |
| SCHEMBL9304542 | 0.87 | BRS3 (0.56) | BRS3AGTR1AGTR2 | |
| SCHEMBL8741191 | 0.81 | BRS3 (0.47) | BRS3AGTR1AGTR2 | |
| SCHEMBL9510826 | 0.81 | BRS3 (0.55) | BRS3AGTR1AGTR2 | |
| SCHEMBL9452730 | 0.77 | BRS3 (0.57) | BRS3AGTR1AGTR2 | |
| SCHEMBL8060271 | 0.75 | BRS3 (0.59) | BRS3AGTR1AGTR2 | |
| SCHEMBL6534729 | 0.74 | BRS3 (0.57) | BRS3AGTR1AGTR2 | |
| SCHEMBL1227544 | 0.74 | BRS3 (0.55) | BRS3AGTR1AGTR2 | |
| SCHEMBL7834869 | 0.74 | DHODH (0.59) | BRS3AGTR1AGTR2 | |
| SCHEMBL6279332 | 0.73 | PPARG (0.55) | BRS3AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525129-A4 | SUBSTITUTED BENZIMIDAZOLES | — | 1993-03-24 | — | — | EP | disclosed |
| EP-0525129-A1 | SUBSTITUTED BENZIMIDAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-03 | — | — | EP | disclosed |