Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12637694 | 0.80 | CYP1A2 (0.40) | PRKCACYP1A2DAGLAALDH1A1 | |
| SCHEMBL14601501 | 0.79 | FAAH (0.35) | — | |
| SCHEMBL16432856 | 0.76 | PRKCA (0.50) | PRKCACYP1A2DAGLAPRKD3PRKCG | |
| SCHEMBL16431984 | 0.76 | PRKCA (0.50) | PRKCACYP1A2DAGLAPRKD3PRKCG | |
| SCHEMBL29512223 | 0.76 | PRKCA (0.50) | PRKCACYP1A2DAGLAPRKD3PRKCG | |
| SCHEMBL11629284 | 0.72 | ALOX5 (0.56) | ALDH1A1 | |
| SCHEMBL14601491 | 0.71 | PRSS1 (0.37) | — | |
| SCHEMBL13177714 | 0.71 | ALDH1A1 (0.47) | PRKCACYP1A2ALDH1A1 | |
| SCHEMBL8045560 | 0.71 | ALDH1A1 (0.47) | PRKCACYP1A2ALDH1A1 | |
| SCHEMBL18614714 | 0.71 | ALDH1A1 (0.47) | PRKCACYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332807-A | Process of producing 8A- and 9A-azalide antibiotics | MERCK & CO., INC. (US) | 1994-07-26 | — | — | US | disclosed |
| WO-1994015617-A1 | 8A-AZA AND 9A-AZA MACROLIDE ANTIBIOTICS, AND A PROCESS FOR PRODUCING SAME AND METHODS OF USE | MERCK & CO., INC. (US) | 1994-07-21 | — | — | WO | disclosed |