Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MERTK | Q12866 | 3/20 | 0.39 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257304 | 0.96 | MERTK (0.44) | MAPK13MAPK12MAPK11MAPK14KDM4E | |
| SCHEMBL9258008 | 0.91 | NAMPT (0.39) | MAPK13MAPK12MAPK11MAPK14KDM4E | |
| Hydrochloric Acid SCHEMBL8138785 | 0.90 | HSD17B10 (0.50) | KDM4ETSHRHSD17B10MERTKMAOA | |
| SCHEMBL9305096 | 0.89 | KDM4E (0.38) | MAPK13MAPK12MAPK11MAPK14KDM4E | |
| SCHEMBL8135725 | 0.89 | LTA4H (0.39) | MAPK13MAPK12MAPK11MAPK14KDM4E | |
| Fumaric Acid SCHEMBL9258073 | 0.89 | HSD17B10 (0.44) | MAPK13MAPK12MAPK11MAPK14KDM4E | |
| Fumaric Acid SCHEMBL9258066 | 0.89 | HSD17B10 (0.44) | MAPK13MAPK12MAPK11MAPK14KDM4E | |
| SCHEMBL9305227 | 0.88 | KIF11 (0.40) | MAPK13MAPK12MAPK11MAPK14KDM4E | |
| SCHEMBL9305127 | 0.85 | MERTK (0.41) | KDM4ETSHRHSD17B10MERTKRPS6KA5 | |
| SCHEMBL9303543 | 0.85 | TEAD2 (0.39) | MAPK13MAPK12MAPK11MAPK14KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296491-A | Pyrazolo[4,3-c]pyridines and their use as serotonin reuptake inhibitors | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-22 | — | — | US | claimed |