Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 3/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8137072 | 0.92 | ALDH1A1 (0.39) | KDM4ETSHRHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL9304792 | 0.89 | MAPK13 (0.41) | KDM4ETSHRHSD17B10MERTKMAPK13 | |
| SCHEMBL8135725 | 0.87 | LTA4H (0.39) | KDM4ETSHRHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL9303549 | 0.87 | KDM4E (0.39) | KDM4ETSHRHSD17B10ALDH1A1MERTK | |
| Hydrochloric Acid SCHEMBL8138785 | 0.85 | HSD17B10 (0.50) | KDM4ETSHRHSD17B10ALDH1A1MERTK | |
| SCHEMBL9257304 | 0.85 | MERTK (0.44) | KDM4ETSHRHSD17B10MERTKMAPK13 | |
| SCHEMBL9305810 | 0.84 | CYP2D6 (0.49) | KDM4ETSHRHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL9305227 | 0.84 | KIF11 (0.40) | KDM4ETSHRHSD17B10MERTKMAPK13 | |
| SCHEMBL8141249 | 0.84 | NAMPT (0.38) | KDM4ETSHRHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL9305127 | 0.83 | MERTK (0.41) | KDM4ETSHRHSD17B10ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296491-A | Pyrazolo[4,3-c]pyridines and their use as serotonin reuptake inhibitors | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-22 | — | — | US | claimed |