Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433888 | 0.83 | MTNR1A (0.54) | NOTUMALDH1A1MTNR1AACENR1D1 | |
| SCHEMBL11392205 | 0.82 | NOTUM (0.48) | NOTUMALDH1A1MTNR1AACENR1D1 | |
| SCHEMBL10246732 | 0.82 | NOTUM (0.48) | NOTUMALDH1A1MTNR1AACENR1D1 | |
| SCHEMBL11622288 | 0.80 | NOTUM (0.47) | NOTUMALDH1A1MTNR1AKDM4ELMNA | |
| SCHEMBL8552879 | 0.80 | ALDH1A1 (0.42) | NOTUMALDH1A1MTNR1AACEKDM4E | |
| SCHEMBL428369 | 0.78 | MTNR1A (0.58) | NOTUMALDH1A1MTNR1AACE | |
| SCHEMBL7435800 | 0.74 | NR1D1 (0.51) | ALDH1A1MTNR1ANR1D1KDM4ELMNA | |
| SCHEMBL11624878 | 0.72 | NOTUM (0.43) | NOTUMALDH1A1KDM4ELMNAGAA | |
| SCHEMBL23343522 | 0.71 | NR1D1 (0.50) | NOTUMNR1D1 | |
| SCHEMBL4959583 | 0.71 | NR1D1 (0.50) | NOTUMNR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324725-A | Antiinflammatory agent, antiallergen | KALI-CHEMIE PHARMA GMBH (DE) | 1994-06-28 | — | — | US | disclosed |