Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 4/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP4 | P49662 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP9 | P55211 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28852929 | 0.88 | ALDH1A1 (0.44) | SNCACASP1CASP3CASP4CASP7 | |
| SCHEMBL9304911 | 0.83 | SNCA (0.47) | SNCACASP1CASP3CASP4CASP7 | |
| Iodide SCHEMBL11686704 | 0.80 | SNCA (0.41) | SNCACASP1CASP3CASP4CASP7 | |
| SCHEMBL11685197 | 0.74 | SNCA (0.37) | SNCACASP1CASP3CASP4CASP7 | |
| SCHEMBL8226386 | 0.73 | SNCA (0.78) | SNCACASP1CASP3CASP4CASP7 | |
| SCHEMBL5476176 | 0.72 | SNCA (0.40) | SNCACASP1CASP3CASP4CASP7 | |
| SCHEMBL27620706 | 0.72 | SNCA (0.42) | SNCACASP1CASP3CASP4CASP7 | |
| SCHEMBL29279287 | 0.70 | CASP1 (0.45) | SNCACASP1CASP3CASP4CASP7 | |
| SCHEMBL30123443 | 0.70 | SNCA (0.49) | SNCACASP1CASP3CASP4CASP7 | |
| SCHEMBL11516459 | 0.69 | SNCA (0.44) | SNCAALDH1A1L3MBTL1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235549-B1 | AGENT FOR COLOURING KERATIN CONTAINING FIBRES | HENKEL KGAA (DE) | 2006-11-29 | — | — | EP | claimed |
| EP-1200051-B1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KGAA (DE) | 2006-02-01 | — | — | EP | claimed |
| US-6790239-B1 | COMBINATION OF AROMATIC ALDEHYDES OR KETONES AND CH-ACTIVE COMPOUNDS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-09-14 | — | — | US | claimed |
| US-6770102-B1 | AROMATIC ALDEHYDES OR KETONES AND CH-ACTIVE COMPOUNDS; DOES NOT REQUIRE OXIDIZING AGENT; BRILLIANCE; COLOR DEPTH; WIDE VARIETY OF SHADES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-08-03 | — | — | US | claimed |
| US-7060109-B2 | Hair dyeing agents containing indigo derivatives | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGA A) (DE) | 2006-06-13 | — | — | US | disclosed |
| US-6790239-B1 | COMBINATION OF AROMATIC ALDEHYDES OR KETONES AND CH-ACTIVE COMPOUNDS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-09-14 | — | — | US | disclosed |
| US-6770102-B1 | AROMATIC ALDEHYDES OR KETONES AND CH-ACTIVE COMPOUNDS; DOES NOT REQUIRE OXIDIZING AGENT; BRILLIANCE; COLOR DEPTH; WIDE VARIETY OF SHADES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-08-03 | — | — | US | disclosed |
| US-20040031108-A1 | Hair dyeing agents containing indigo derivatives | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2004-02-19 | — | — | US | disclosed |
| EP-0161789-B1 | CYANINE AND MEROCYANINE SPECTRAL SENSITIZING DYES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-09-06 | — | — | EP | disclosed |
| US-4701398-A | CYANINE AND/OR MEROCYANINE DYES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-10-20 | — | — | US | disclosed |
| US-4614801-A | Direct positive dyes made from 3-indolizine carboxaldehyde | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-09-30 | — | — | US | disclosed |
| US-4145537-A | BENZOTHIAZOLIUM DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040031108-A1 | Hair dyeing agents containing indigo derivatives | KRT18, BBOX1, BRDT | SNCA 4493/4885CASP1 3127/4885CASP3 1524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.