Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11108801 | 0.82 | SCN4A (0.44) | CSNK1DEPHX2SCN4APPARADYRK1A | |
| SCHEMBL9304400 | 0.82 | KMT2A (0.49) | CSNK1DEPHX2SCN4ASHBGPPARA | |
| SCHEMBL1747959 | 0.76 | EPHX2 (0.65) | CSNK1DEPHX2SCN4APPARADYRK1A | |
| SCHEMBL10762518 | 0.73 | PPARA (0.48) | CSNK1DPPARADYRK1AACP1SMN1; SMN2 | |
| SCHEMBL9306454 | 0.73 | CSNK1D (0.39) | CSNK1DPPARADYRK1AACP1ALDH1A1 | |
| SCHEMBL9306457 | 0.71 | CSNK1D (0.35) | CSNK1DEPHX2SCN4ASHBGPPARA | |
| SCHEMBL10762513 | 0.71 | PPARA (0.48) | CSNK1DPPARADYRK1ASMN1; SMN2MAPT | |
| SCHEMBL9306032 | 0.70 | SHBG (0.39) | CSNK1DSHBGCYP3A4CYP2D6HIF1A | |
| SCHEMBL9304978 | 0.70 | SCN10A (0.43) | CSNK1DSHBGDYRK1ACYP3A4CYP2D6 | |
| SCHEMBL1094500 | 0.70 | APP (0.47) | EPHX2SCN4ASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0129506-B1 | HETEROCYCLICALLY SUBSTITUTED THIO(CYCLO)ALKANE POLYCARBOXYLIC ACIDS | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | disclosed |
| EP-0129506-A2 | Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |