Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | CBFB | Q13951 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PTPRF | P10586 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305034 | 0.87 | CBFB (0.56) | PDE3BPDE3ACBFBNPC1RAB9A | |
| SCHEMBL3149598 | 0.83 | MEN1 (0.42) | PDE3BPDE3ANPC1RAB9AKLF5 | |
| SCHEMBL1193199 | 0.81 | ALDH1A1 (0.48) | PDE3BPDE3ANPC1RAB9AALDH1A1 | |
| SCHEMBL9305942 | 0.81 | PDE3B (0.46) | PDE3BPDE3ACBFBNPC1RAB9A | |
| SCHEMBL9304866 | 0.77 | MAPT (0.49) | PDE3BPDE3ACBFBNPC1RAB9A | |
| SCHEMBL9940567 | 0.75 | MLKL (0.43) | NPC1RAB9AHDAC3HDAC1HDAC2 | |
| SCHEMBL30167015 | 0.74 | KMT2A (0.47) | NPC1RAB9AALDH1A1KMT2ALMNA | |
| SCHEMBL1193332 | 0.74 | RUNX1 (0.43) | CBFBNPC1RAB9AMAPK1KMT2A | |
| SCHEMBL30312561 | 0.74 | PDE3B (0.40) | PDE3BPDE3ACBFBNPC1RAB9A | |
| SCHEMBL15646693 | 0.73 | MEN1 (0.57) | PDE3BPDE3ACBFBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |