Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | PIM1 | P11309 | 4/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305829 | 0.92 | TDP1 (0.41) | CSNK2A2CSNK2BMAOAMAOBDHODH | |
| SCHEMBL8138791 | 0.86 | CSNK2A2 (0.39) | CSNK2A2CSNK2BMAOAMAOBACHE | |
| SCHEMBL9305230 | 0.86 | MAOA (0.36) | MAOAMAOBACHETDP1 | |
| SCHEMBL8134219 | 0.86 | CDC7 (0.41) | MAOAMAOBACHEMERTKTDP1 | |
| Hydrochloric Acid SCHEMBL8138778 | 0.85 | TDP1 (0.36) | MAOAMAOBACHETDP1 | |
| SCHEMBL9306122 | 0.83 | HSD17B10 (0.47) | MAOAMAOBACHEMERTK | |
| SCHEMBL9305086 | 0.83 | AXL (0.39) | MERTKTDP1ADORA2A | |
| Hydrochloric Acid SCHEMBL8134231 | 0.82 | HSD17B10 (0.46) | MAOAMAOBACHEMERTK | |
| SCHEMBL9304005 | 0.81 | P2RX7 (0.38) | MAOA | |
| SCHEMBL9258008 | 0.80 | NAMPT (0.39) | MAOAMAOBACHEMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296491-A | Pyrazolo[4,3-c]pyridines and their use as serotonin reuptake inhibitors | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-22 | — | — | US | claimed |