Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.32 |
| ▸ | BID | P55957 | 3/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.32 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.32 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305430 | 0.84 | S1PR2 (0.34) | TSHRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL9443096 | 0.77 | GPR35 (0.35) | TSHRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL9305489 | 0.75 | KCNH2 (0.35) | TSHRKMT2AKDM4EMEN1GAA | |
| SCHEMBL9305250 | 0.72 | KCNH2 (0.35) | TSHRKMT2AKDM4EMEN1GAA | |
| SCHEMBL9733955 | 0.68 | SMN1; SMN2 (0.32) | KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9443100 | 0.64 | GPR35 (0.35) | TSHRCYSLTR2CYSLTR1KMT2AMEN1 | |
| SCHEMBL9305580 | 0.64 | ALDH1A1 (0.42) | KMT2AKDM4EMEN1GAAHTT | |
| SCHEMBL9304858 | 0.62 | RAB9A (0.52) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL10893421 | 0.62 | RAB9A (0.49) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL9307086 | 0.62 | S1PR1 (0.44) | KAT8PPARGPPARAGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |