Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28219381 | 0.77 | ACLY (0.57) | HSPD1BLMHSPE1CPT2ACLY | |
| SCHEMBL14920851 | 0.76 | HSPD1 (0.38) | ALDH1A1HSPD1BLMHSPE1CPT2 | |
| SCHEMBL7050626 | 0.74 | CPT2 (0.39) | ALDH1A1HSPD1BLMHSPE1CPT2 | |
| SCHEMBL9358019 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MAPTPTGS1HSD17B10SLC1A2 | |
| SCHEMBL6270504 | 0.74 | ACLY (0.59) | ALDH1A1MAPTPTGS1HSPD1BLM | |
| SCHEMBL5969708 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MAPTPTGS1HSPD1BLM | |
| SCHEMBL6262487 | 0.72 | PTGS1 (0.52) | ALDH1A1MAPTPTGS1HSD17B10SLC1A2 | |
| SCHEMBL28261059 | 0.71 | CPT2 (0.40) | ALDH1A1MAPTPTGS1HSPD1BLM | |
| SCHEMBL24015558 | 0.71 | ALDH1A1 (0.45) | ALDH1A1MAPTPTGS1MEN1KMT2A | |
| SCHEMBL6262500 | 0.71 | PTGS1 (0.56) | ALDH1A1MAPTPTGS1HSD17B10SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0495265-B1 | Acid-labile linker molecules | AKZO NOBEL NV (NL) | 1994-08-03 | — | — | EP | disclosed |
| US-5306809-A | Cancer immune therapy | AKZO N.V. (NL) | 1994-04-26 | — | — | US | disclosed |
| EP-0495265-A1 | Acid-labile linker molecules | Akzo Nobel N.V. (NL) | 1992-07-22 | — | — | EP | disclosed |