Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304859 | 1.00 | TACR1 (0.45) | TACR1LNPEPMDM4MDM2CYP3A4 | |
| SCHEMBL21627155 | 0.87 | TACR1 (0.44) | TACR1LNPEPTAS1R3TAS1R1ERAP2 | |
| SCHEMBL10477398 | 0.87 | CYP3A4 (0.42) | TACR1CYP3A4TDP1TAS1R3TAS1R1 | |
| SCHEMBL18655444 | 0.84 | LMNA (0.45) | TACR1SMN1; SMN2 | |
| SCHEMBL16870009 | 0.84 | TACR1 (0.40) | TACR1LCKTAS1R3TAS1R1 | |
| SCHEMBL9305186 | 0.84 | TACR1 (0.40) | TACR1LCKTAS1R3TAS1R1 | |
| SCHEMBL10477507 | 0.83 | TACR1 (0.46) | TACR1TAS1R3TAS1R1 | |
| SCHEMBL23375845 | 0.82 | KLK5 (0.47) | TACR1MDM4MDM2SMN1; SMN2 | |
| SCHEMBL28569264 | 0.82 | KLK5 (0.47) | TACR1MDM4MDM2SMN1; SMN2 | |
| SCHEMBL5115246 | 0.76 | OPRD1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364850-A | Analgesics | G. D. SEARLE & CO. (US) | 1994-11-15 | — | — | US | disclosed |
| US-5272175-A | Substituted tyrosyl diamide compounds | G. D. SEARLE & CO. (US) | 1993-12-21 | — | — | US | disclosed |