Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 9/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5115242 | 1.00 | OPRD1 (0.46) | OPRD1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL5775220 | 0.98 | OPRD1 (0.46) | OPRD1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL5775227 | 0.98 | OPRD1 (0.46) | OPRD1OPRM1OPRK1 | |
| SCHEMBL30162392 | 0.87 | CYP3A4 (0.46) | OPRD1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL20236002 | 0.87 | ALDH1A1 (0.43) | OPRM1 | |
| Hydrochloric Acid SCHEMBL20236003 | 0.87 | ALDH1A1 (0.43) | OPRM1 | |
| SCHEMBL25469337 | 0.85 | OPRD1 (0.45) | OPRD1OPRM1OPRK1 | |
| SCHEMBL21096380 | 0.83 | OPRM1 (0.47) | OPRD1OPRM1OPRK1 | |
| SCHEMBL21473716 | 0.81 | GPR35 (0.38) | OPRD1OPRM1OPRK1 | |
| SCHEMBL24012345 | 0.81 | ALDH1A1 (0.40) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439258-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM (CANADA) LTD (CA) | 2008-10-21 | — | — | US | disclosed |
| US-7439258-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM (CANADA) LTD (CA) | 2008-10-21 | — | — | US | disclosed |
| US-7439258-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM (CANADA) LTD (CA) | 2008-10-21 | — | — | US | disclosed |