Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554899 | 0.82 | EPHX1 (0.44) | SMN1; SMN2ALDH1A1GAAEPHX1SIGMAR1 | |
| SCHEMBL1554221 | 0.80 | ALDH1A1 (0.48) | EPHX2SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL22346683 | 0.78 | GBA2 (0.43) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8435167 | 0.77 | GBA2 (0.43) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL10872430 | 0.72 | MEN1 (0.66) | EPHX2SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL23989211 | 0.68 | SMN1; SMN2 (0.74) | EPHX2SMN1; SMN2ALDH1A1EPHX1 | |
| SCHEMBL7494872 | 0.68 | SMN1; SMN2 (0.74) | EPHX2SMN1; SMN2ALDH1A1EPHX1 | |
| SCHEMBL931682 | 0.67 | SIGMAR1 (0.46) | EPHX2SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL2801497 | 0.67 | EPHX1 (0.67) | EPHX2SMN1; SMN2GAAEPHX1 | |
| SCHEMBL22055472 | 0.67 | SMN1; SMN2 (0.78) | EPHX2SMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | disclosed |