Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22346683 | 0.87 | GBA2 (0.43) | GBA2SMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL29639440 | 0.78 | GBA2 (0.50) | GBA2SMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL930567 | 0.77 | EPHX2 (0.43) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL24402308 | 0.76 | HSD11B1 (0.47) | CHRM2CHRM1CHRM3 | |
| SCHEMBL12144704 | 0.76 | HSD11B1 (0.47) | CHRM2CHRM1CHRM3 | |
| SCHEMBL7788793 | 0.74 | GBA2 (0.51) | GBA2SMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL13662149 | 0.73 | CHRNB2 (0.39) | TSHR | |
| SCHEMBL1554770 | 0.72 | CHRNB2 (0.48) | GBA2SMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL20241634 | 0.72 | GBA2 (0.42) | GBA2SMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL20899545 | 0.72 | LMNA (0.37) | GBA2SMN1; SMN2LMNAPOLBECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040214837-A1 | Cannabinoid receptor ligands and uses thereof | PFIZER INC. | 2004-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214837-A1 | Cannabinoid receptor ligands and uses thereof | CNR1, CNR2, GPR18 | GBA2 1165/4885SMN1; SMN2 3678/4885LMNA 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.