⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1208291 | 0.68 | — | — | |
| SCHEMBL15967513 | 0.62 | — | — | |
| SCHEMBL183498 | 0.62 | — | — | |
| SCHEMBL27684488 | 0.61 | KDM4E (0.50) | — | |
| SCHEMBL6961571 | 0.60 | — | — | |
| SCHEMBL518616 | 0.60 | KDM4E (0.31) | — | |
| Benzene SCHEMBL27632184 | 0.60 | SIGMAR1 (0.44) | — | |
| SCHEMBL1208195 | 0.60 | — | — | |
| SCHEMBL12671511 | 0.60 | CA2 (0.35) | — | |
| SCHEMBL8467 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 528 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343036-A | Isochroman compound, and pharmaceutical composition and application thereof | 江苏联环药业股份有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-115835910-A | Hydrogenated isoquinoline or naphthyridine compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2023-03-21 | — | — | CN | claimed |
| US-20240238460-A1 | IMPROVED PROSTATE-SPECIFIC MEMBRANE ANTIGEN TARGETING RADIOPHARMACEUTICALS AND USES THEREOF | TELIX PHARMACEUTICALS INNOVATIONS PTY LTD (AU) | 2024-07-18 | — | — | US | disclosed |
| CN-118339205-A | Polymerization process using dual catalyst composition | 道达尔能源一技术比利时公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-118339204-A | Dual catalyst composition | 道达尔能源一技术比利时公司 | 2024-07-12 | — | — | CN | disclosed |
| WO-2024146923-A1 | TUBULIN POLYMERIZATION INHIBITORS | AB SCIENCE (FR) | 2024-07-11 | — | — | WO | disclosed |
| US-12030866-B2 | 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD | SPRINGWORKS THERAPEUTICS, INC. (US) | 2024-07-09 | — | — | US | disclosed |
| CN-118317983-A | Dual catalyst composition | 道达尔能源一技术比利时公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-118302425-A | IRAK4 inhibitors and uses thereof | 武汉人福创新药物研发中心有限公司 | 2024-07-05 | — | — | CN | disclosed |
| US-20240209127-A1 | NEW METALLOCENE CATALYST AND USE THEREOF | TOTALENERGIES ONETECH BELGIUM (BE) | 2024-06-27 | — | — | US | disclosed |
| US-12011454-B2 | Nicotinamide mononucleotide derivatives and use thereof in the treatment and prevention of a red blood cell disorder | NUVAMID SA (CH) | 2024-06-18 | — | — | US | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |
| US-20050256176-A1 | Sulphonamide derivatives and their use as tace inhibitors | ASTAZENECA AB (SE) | 2005-11-17 | — | — | US | disclosed |
| WO-2005085232-A1 | HYDANTOIN DERIVATIVES FOR USE AS TACE AND AGGRECANASE INHIBITORS | ASTRAZENECA AB (SE) | 2005-09-15 | — | — | WO | disclosed |
| EP-1551826-A1 | HYDANTOINE DERIVATIVES AND THEIR USE AS TACE INHIBITORS | Astrazeneca AB (SE) | 2005-07-13 | — | — | EP | disclosed |
| EP-1539740-A1 | SULPHONAMIDE DERIVATIVES AND THEIR USE AS TACE INHIBITORS | AstraZeneca AB (SE) | 2005-06-15 | — | — | EP | disclosed |
| EP-1539159-A1 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ARYL OR HETEROARYL GROUP FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | Astrazeneca AB (SE) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004024721-A1 | HYDANTOIN DERIVATIVES UND DEREN VERWENDUNG ALS TACE INHIBITOREN | ASTRAZENECA AB (SE) | 2004-03-25 | — | — | WO | disclosed |
| WO-2004024715-A1 | SULPHONAMIDE DERIVATIVES AND THEIR USE AS TACE INHIBITORS | ASTRAZENECA AB (SE) | 2004-03-25 | — | — | WO | disclosed |
| WO-2004006926-A1 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ARYL OR HETEROARYL GROUP FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2004-01-22 | — | — | WO | disclosed |