Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Dodecanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetradecane SCHEMBL98195 | 0.92 | TP53 (0.52) | MEN1KMT2ATP53CA1CA2 | |
| Dodecanol SCHEMBL3285087 | 0.86 | LMNA (0.56) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| Dodecanol SCHEMBL27573175 | 0.86 | LMNA (0.56) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| 1-Hexanol SCHEMBL29111134 | 0.84 | LMNA (0.59) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| Cetostearyl Alcohol SCHEMBL28094788 | 0.84 | LMNA (0.59) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| Cetyl Alcohol SCHEMBL1360724 | 0.83 | LMNA (0.72) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| Myristyl Alcohol SCHEMBL4612309 | 0.83 | LMNA (0.72) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| Sulfuric Acid SCHEMBL5510760 | 0.83 | LMNA (0.72) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| Octanol SCHEMBL208036 | 0.83 | LMNA (0.72) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| 1-Hexanol SCHEMBL8015503 | 0.83 | LMNA (0.72) | LMNAALDH1A1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352389-A | Aqueous solutions of oil in water emulsions containing low molecular weight saturated aliphatic alkylamines, their hydroxy derivatives and/or basic aminoacids bufferd at pH 7-8.5 | CRINOS INDUSTRIA FARMACOBIOLOGICA SPA (IT) | 1994-10-04 | — | — | US | disclosed |
| EP-0530865-A1 | Composition for the cleaning of skin, scalp and hair | Crinos Industria Farmacobiologica S.p.A. (IT) | 1993-03-10 | — | — | EP | disclosed |