Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | KYNU | Q16719 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305772 | 0.94 | ITGB3 (0.56) | ITGB3ITGA2BMAPTLMNAITGAV | |
| SCHEMBL8668133 | 0.81 | SIRT2 (0.52) | ITGB3ITGA2BMAPTLMNAALDH1A1 | |
| SCHEMBL7283088 | 0.78 | ITGB3 (0.74) | ITGB3ITGA2BLMNAALDH1A1ITGAV | |
| SCHEMBL8668099 | 0.77 | MEN1 (0.54) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL30070644 | 0.71 | LMNA (0.60) | MAPTLMNAALDH1A1ALOX15CTSK | |
| SCHEMBL30825625 | 0.71 | ALDH1A1 (0.58) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL8674043 | 0.71 | ALDH1A1 (0.58) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL7151822 | 0.70 | ALDH1A1 (0.74) | MAPTALDH1A1CYP3A4TSHRMEN1 | |
| SCHEMBL329686 | 0.70 | ALDH1A1 (0.74) | MAPTALDH1A1CYP3A4TSHRMEN1 | |
| SCHEMBL5561531 | 0.70 | ALDH1A1 (0.60) | MAPTALDH1A1CYP3A4TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294616-A | Anticoagulants, inhibition of fibrinogen binding to blood platelets | MERCK & CO., INC. (US) | 1994-03-15 | — | — | US | disclosed |