Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306979 | 0.85 | HPGD (0.56) | HPGDHSD17B10TP53TSHRPLA2G4B | |
| Iodide SCHEMBL9565573 | 0.80 | — | — | |
| SCHEMBL9306397 | 0.78 | SMPD1 (0.52) | — | |
| SCHEMBL9308491 | 0.78 | THRA (0.51) | PLA2G4B | |
| SCHEMBL9306393 | 0.77 | HPGD (0.54) | HPGDHSD17B10PLK1TP53TSHR | |
| SCHEMBL9308107 | 0.74 | TRPM8 (0.55) | HPGDHSD17B10TP53TSHRPLA2G4B | |
| SCHEMBL9306665 | 0.74 | SMPD1 (0.51) | PLA2G4B | |
| SCHEMBL8085972 | 0.74 | — | — | |
| SCHEMBL9308154 | 0.74 | HSD17B10 (0.52) | HPGDHSD17B10TP53TSHRPLA2G4B | |
| SCHEMBL9306473 | 0.73 | HPGD (0.51) | HPGDHSD17B10TSHRTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5208247-A | Antianaphylactic agents or septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0530444-A1 | Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |