SCHEMBL9306322

SCHEMBL9306322

CC([C@H](O[SiH](C)C)C(=O)O)C(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
MMP9 P14780 1/20 0.34
MMP13 P45452 1/20 0.34
SLC1A3 P43003 1/20 0.30
SLC1A2 P43004 1/20 0.30
SLC1A1 P43005 1/20 0.30
SLC7A5 Q01650 1/20 0.30
PGD P52209 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5990687 1.00 MMP1 (0.34) MMP1MMP2MMP3MMP9MMP13
SCHEMBL5990675 1.00 MMP1 (0.34) MMP1MMP2MMP3MMP9MMP13
SCHEMBL10653722 0.80 SMN1; SMN2 (0.42)
SCHEMBL10652589 0.77
SCHEMBL9274702 0.75 MMP1 (0.32) MMP1MMP2MMP3MMP9MMP13
SCHEMBL9432002 0.73 TSHR (0.36) SLC1A3SLC1A2SLC1A1
SCHEMBL10860789 0.73 MMP1 (0.31) MMP1MMP2MMP3MMP9MMP13
SCHEMBL8181710 0.73 MMP1 (0.34) MMP1MMP2MMP3MMP9MMP13
SCHEMBL8181713 0.73 MMP1 (0.34) MMP1MMP2MMP3MMP9MMP13
SCHEMBL8190952 0.73 MMP1 (0.34) MMP1MMP2MMP3MMP9MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5332807-A Process of producing 8A- and 9A-azalide antibiotics MERCK & CO., INC. (US) 1994-07-26 US disclosed
WO-1994015617-A1 8A-AZA AND 9A-AZA MACROLIDE ANTIBIOTICS, AND A PROCESS FOR PRODUCING SAME AND METHODS OF USE MERCK & CO., INC. (US) 1994-07-21 WO disclosed
US-5149462-A Used as ferroelectric liquid crystal MITSUBISHI RAYON COMPANY LTD. (JP) 1992-09-22 US disclosed