Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
| ▸ | PGD | P52209 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5990687 | 1.00 | MMP1 (0.34) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL9306322 | 1.00 | MMP1 (0.34) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL10653722 | 0.80 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL10652589 | 0.77 | — | — | |
| SCHEMBL9274702 | 0.75 | MMP1 (0.32) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL9432002 | 0.73 | TSHR (0.36) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10860789 | 0.73 | MMP1 (0.31) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL8181710 | 0.73 | MMP1 (0.34) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL8181713 | 0.73 | MMP1 (0.34) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL8190952 | 0.73 | MMP1 (0.34) | MMP1MMP2MMP3MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11234953-B2 | Ketone bodies to protect tissues from damage by ionizing radiation | TDELTAS LIMITED (GB) | 2022-02-01 | — | — | US | disclosed |
| US-11230722-B2 | Nutritional supplements and therapeutic compositions comprising (r)-3-hydroxybutyrate derivatives | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2022-01-25 | — | — | US | disclosed |
| US-20200215016-A1 | Ketone Bodies To Protect Tissues From Damage By Ionizing Radiation | TDELTAS (GB) | 2020-07-09 | — | — | US | disclosed |
| EP-3659595-A1 | KETONE BODIES TO PROTECT TISSUES FROM DAMAGE BY IONIZING RADIATION | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services (US) | 2020-06-03 | — | — | EP | disclosed |
| US-10478415-B2 | Ketone bodies to protect tissues from damage by ionizing radiation | TDELTAS LIMITED (GB) | 2019-11-19 | — | — | US | disclosed |
| EP-2914251-B1 | KETONE BODIES TO PROTECT TISSUES FROM DAMAGE BY IONIZING RADIATION | US HEALTH (US) | 2019-08-21 | — | — | EP | disclosed |
| US-20180195096-A1 | Nutritional supplements and therapeutic compositions comprising (r)-3- hydroxybutyrate derivatives | UNIV OXFORD INNOVATION LTD (GB) | 2018-07-12 | — | — | US | disclosed |
| EP-1648952-B1 | NUTRITIONAL SUPPLEMENTS AND THERAPEUTIC COMPOSITIONS COMPRISING (R)-3-HYDROXYBUTYRATE DERIVATIVES | THE US GOV AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-03-07 | — | — | EP | disclosed |
| US-20170196827-A1 | Ketone Bodies To Protect Tissues From Damage By Ionizing Radiation | TDELTAS (GB) | 2017-07-13 | — | — | US | disclosed |
| US-9579302-B2 | Ketone bodies to protect tissues from damage by ionizing radiation | TDELTAS (GB) | 2017-02-28 | — | — | US | disclosed |
| EP-0224059-B1 | AZETIDINONE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-04-15 | — | — | EP | disclosed |
| US-5081238-A | βmethyl azetidinone derivatives and stereoselective process for preparing the same | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0409066-A2 | Optically active compound for liquid crystal and its use | MITSUBISHI RAYON COMPANY, LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |
| EP-0209886-B1 | BETA-N-SUBSTITUTED AMINOTHIOL ESTER AND PROCESS FOR PREPARING THE SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1990-03-21 | — | — | EP | disclosed |
| EP-0181581-B1 | BETA-AMINOTHIOL ESTER AND PROCESS FOR PREPARING THEREOF | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1988-07-13 | — | — | EP | disclosed |
| US-4728746-A | INTERMEDIATES FOR CARBAPENICILLINS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1988-03-01 | — | — | US | disclosed |
| US-4709064-A | ANTIBIOTIC INTERMEDIATES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1987-11-24 | — | — | US | disclosed |
| EP-0224059-A1 | Azetidinone derivative and process for preparing the same | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1987-06-03 | — | — | EP | disclosed |
| EP-0209886-A2 | beta-N-substituted aminothiol ester and process for preparing the same | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1987-01-28 | — | — | EP | disclosed |
| EP-0181581-A1 | beta-Aminothiol ester and process for preparing thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-05-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11234953-B2 | Ketone bodies to protect tissues from damage by ionizing radiation | ACACB, BCKDK, ACACA | MMP1 995/4885MMP2 2868/4885MMP3 1656/4885 |
| US-10478415-B2 | Ketone bodies to protect tissues from damage by ionizing radiation | ACACB, BCKDK, ACACA | MMP1 995/4885MMP2 2868/4885MMP3 1656/4885 |
| US-20170196827-A1 | Ketone Bodies To Protect Tissues From Damage By Ionizing Radiation | ACACB, BCKDK, ACACA | MMP1 995/4885MMP2 2868/4885MMP3 1656/4885 |
| US-11230722-B2 | Nutritional supplements and therapeutic compositions comprising (r)-3-hydroxybutyrate derivatives | BCHE, LIPC, ACACB | MMP1 2333/4885MMP2 1024/4885MMP3 694/4885 |
| US-20180195096-A1 | Nutritional supplements and therapeutic compositions comprising (r)-3- hydroxybutyrate derivatives | BCHE, LIPC, ACACB | MMP1 2333/4885MMP2 1024/4885MMP3 694/4885 |
| US-20200215016-A1 | Ketone Bodies To Protect Tissues From Damage By Ionizing Radiation | ACACB, BCKDK, ACACA | MMP1 995/4885MMP2 2868/4885MMP3 1656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.