Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 9/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 9/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306409 | 1.00 | CYP1A1 (0.35) | CYP1A1CYP1B1CYP1A2MAPTKDM4E | |
| SCHEMBL8316004 | 0.86 | FGF23 (0.36) | CYP1A2MAPTKDM4ELMNAMEN1 | |
| SCHEMBL8316008 | 0.86 | FGF23 (0.36) | CYP1A2MAPTKDM4ELMNAMEN1 | |
| SCHEMBL8313756 | 0.84 | KDM4E (0.34) | CYP1A2MAPTKDM4ELMNAMEN1 | |
| SCHEMBL8313753 | 0.84 | KDM4E (0.34) | CYP1A2MAPTKDM4ELMNAMEN1 | |
| SCHEMBL8310781 | 0.83 | RAB9A (0.38) | CYP1A2MAPTKDM4ELMNAMEN1 | |
| SCHEMBL8310785 | 0.83 | RAB9A (0.38) | CYP1A2MAPTKDM4ELMNAMEN1 | |
| SCHEMBL8316359 | 0.83 | MAPT (0.47) | CYP1A2MAPTKDM4ELMNAMEN1 | |
| SCHEMBL8315650 | 0.83 | LMNA (0.39) | MAPTKDM4ELMNAMEN1HTT | |
| SCHEMBL8316372 | 0.83 | MAPT (0.47) | CYP1A2MAPTKDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300639-A | 2-oxo-3-carbonylamino-substituted azepine intermediates; lipoperoxide formation inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-05 | — | — | US | disclosed |