Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.61 |
| ▸ | RAB9A | P51151 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9443262 | 0.92 | NPC1 (0.60) | NPC1RAB9AALDH1A1LMNAHTT | |
| SCHEMBL9443272 | 0.91 | NPC1 (0.58) | NPC1RAB9AALDH1A1LMNAHTT | |
| SCHEMBL9443265 | 0.85 | NPC1 (0.58) | NPC1RAB9AALDH1A1LMNAHTT | |
| SCHEMBL9443270 | 0.80 | PPARA (0.59) | NPC1RAB9AALDH1A1LMNAHTT | |
| SCHEMBL9306676 | 0.78 | HDAC6 (0.46) | NPC1RAB9ASMN1; SMN2HDAC1DYRK1A | |
| SCHEMBL2856934 | 0.78 | HPGD (0.56) | NPC1RAB9AALDH1A1HTTPOLB | |
| SCHEMBL9304603 | 0.78 | LDHA (0.45) | NPC1RAB9ALMNAHTTMAPT | |
| SCHEMBL9305825 | 0.76 | NPC1 (0.72) | NPC1RAB9AALDH1A1LMNAHTT | |
| SCHEMBL9304734 | 0.73 | ALDH1A1 (0.51) | NPC1RAB9AALDH1A1HTTMAPT | |
| SCHEMBL10759303 | 0.73 | NPC1 (0.63) | NPC1RAB9AALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |