Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 12/20 | 0.45 |
| ▸ | INSR | P06213 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 2/20 | 0.41 |
| ▸ | GSR | P00390 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9443201 | 0.81 | ALDH1A1 (0.41) | ALDH1A1GAAL3MBTL1APPMAPK1 | |
| SCHEMBL9443212 | 0.81 | ALDH1A1 (0.43) | ALDH1A1GAAL3MBTL1APPMAPK1 | |
| SCHEMBL9304603 | 0.80 | LDHA (0.45) | APPSMN1; SMN2MAPTHTTTP53 | |
| SCHEMBL9443249 | 0.77 | HPGD (0.38) | GAASMN1; SMN2PKMKDM4EMEN1 | |
| SCHEMBL2856934 | 0.77 | HPGD (0.56) | ALDH1A1GAAMAPK1SMN1; SMN2PKM | |
| SCHEMBL9443260 | 0.76 | PKM (0.38) | GAASMN1; SMN2PKMKDM4EHTT | |
| SCHEMBL9306676 | 0.73 | HDAC6 (0.46) | THRBSMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL9306437 | 0.73 | NPC1 (0.61) | ALDH1A1MAPK1RECQLSMN1; SMN2MAPT | |
| SCHEMBL8972395 | 0.72 | RAB9A (0.48) | ALDH1A1SMN1; SMN2TDP1MAPTKDM4E | |
| SCHEMBL8973268 | 0.72 | MEN1 (0.44) | ALDH1A1GAAAPPTHRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |