Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 6/20 | 0.33 |
| ▸ | IL2 | P60568 | 6/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.32 |
| ▸ | ITGAL | P20701 | 2/20 | 0.32 |
| ▸ | FPR2 | P25090 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522871 | 0.83 | TNF (0.43) | FOLH1ALBOPRK1TNFITGB2 | |
| SCHEMBL9522481 | 0.81 | FOLH1 (0.41) | FOLH1ALBIL2OPRK1ITGB2 | |
| SCHEMBL169323 | 0.77 | LMNA (0.54) | MEN1KMT2AKDM4EUSP2EGFR | |
| SCHEMBL5319562 | 0.77 | LMNA (0.54) | MEN1KMT2AKDM4EUSP2EGFR | |
| SCHEMBL11356756 | 0.74 | KDM6B (0.33) | MEN1KMT2AKDM6BKDM4EUSP2 | |
| SCHEMBL14151451 | 0.73 | FOLH1 (0.64) | FOLH1MEN1KMT2AALBIL2 | |
| SCHEMBL32662363 | 0.72 | KDM6B (0.60) | FOLH1MEN1KMT2AOPRK1KDM6B | |
| SCHEMBL18800390 | 0.72 | KDM6B (0.60) | FOLH1MEN1KMT2AOPRK1KDM6B | |
| SCHEMBL1115191 | 0.69 | PCNA (0.52) | MEN1KMT2A | |
| SCHEMBL55971 | 0.69 | FOLH1 (0.56) | FOLH1MEN1KMT2ASLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279812-A | Polypeptide; amino acid sequence of hirudin | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-01-18 | — | — | US | disclosed |