SCHEMBL169323

SCHEMBL169323

NC(Cc1ccc(O)c(I)c1I)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.54
KDM4E B2RXH2 4/20 0.54
THRB P10828 4/20 0.54
KMT2A Q03164 4/20 0.54
USP2 O75604 3/20 0.54
HIF1A Q16665 3/20 0.54
ALOX15 P16050 3/20 0.54
HSD17B10 Q99714 3/20 0.54
MEN1 O00255 3/20 0.54
MAPT P10636 3/20 0.54
BLM P54132 3/20 0.54
PMP22 Q01453 3/20 0.54
NPSR1 Q6W5P4 3/20 0.54
RECQL P46063 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
PKM P14618 2/20 0.54
CYP3A4 P08684 2/20 0.54
NFKB1 P19838 2/20 0.54
ALDH1A1 P00352 2/20 0.54
RGS12 O14924 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5319562 1.00 LMNA (0.54) LMNAKDM4ETHRBKMT2AUSP2
SCHEMBL1742705 0.90 THRB (0.45) LMNAKDM4ETHRBKMT2AUSP2
SCHEMBL1274573 0.90 THRB (0.45) LMNAKDM4ETHRBKMT2AUSP2
SCHEMBL20299961 0.85 THRB (0.50) LMNAKDM4ETHRBKMT2AUSP2
SCHEMBL11742941 0.80 THRB (0.42) LMNAKDM4ETHRBKMT2AUSP2
SCHEMBL4926007 0.79 THRB (0.41) LMNAKDM4ETHRBKMT2AUSP2
SCHEMBL29216329 0.79 KDM4E (0.58) LMNAKDM4ETHRBKMT2AUSP2
SCHEMBL454801 0.79 KDM4E (0.58) LMNAKDM4ETHRBKMT2AUSP2
SCHEMBL6694580 0.77 SCN9A (0.37) LMNAKDM4ETHRBKMT2AUSP2
SCHEMBL9306542 0.77 FOLH1 (0.36) KDM4EKMT2AUSP2HIF1AALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12546788-B2 Methods for differentiating destructive thyroiditis from other pathological conditions ASKA PHARMACEUTICAL CO., LTD. (JP) 2026-02-10 US claimed
US-12540403-B2 Stable composition for catalytic deposition of silver SWISSTO12 SA (CH) 2026-02-03 US claimed
US-12480021-B2 Composition for semiconductor process, method for preparing the same and method for preparing semiconductor device using the same SK ENPULSE CO., LTD. (KR) 2025-11-25 US claimed
US-20240301558-A1 STABLE COMPOSITION FOR CATALYTIC DEPOSITION OF SILVER SWISSTO12 SA (CH) 2024-09-12 US claimed
CN-116077712-B Graphene composite microsphere, preparation method thereof, embolic material and pharmaceutical preparation 北京石墨烯技术研究院有限公司 2024-08-16 CN claimed
CN-115156529-B Silver-coated copper powder and preparation method thereof 苏州大学 2024-06-28 CN claimed
CN-117554536-B Simultaneous analysis method for 15 thyroid hormones in environmental water sample 北京林业大学 2024-03-19 CN claimed
CN-117554536-A Simultaneous analysis method for 15 thyroid hormones in environmental water sample 北京林业大学 2024-02-13 CN claimed
WO-2023234809-A1 METHOD FOR PREVENTING IODINE RADIONUCLIDE DAMAGE TO THE HUMAN OR ANIMAL BODY АНДРЕЙЧУК, ВАСИЛИЙ ПЕТРОВИЧ 2023-12-07 WO claimed
US-20230305016-A1 TEST KIT AND METHOD OF DETERMINING TRYPTOPHAN IN EXTRACTS OF FAECAL SAMPLES IMMUNDIAGNOSTIK AG (DE) 2023-09-28 US claimed
WO-1997046541-A2 USE OF TRIAZINE-BASED UVAs FOR USE AS QUENCHERS IN PAPER-MAKING PROCESSES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1997-12-11 WO claimed
EP-0599908-B1 NEW GANGLIOSIDE DERIVATIVES FIDIA SPA (IT) 1997-03-12 EP claimed
EP-0649325-A4 ADMINISTRATION OF MEDICAMENTS TO POULTRY. SANOFI ANIMAL HEALTH INC (US) 1995-08-23 EP claimed
EP-0649325-A1 ADMINISTRATION OF MEDICAMENTS TO POULTRY SANOFI ANIMAL HEALTH, Inc. (US) 1995-04-26 EP claimed
US-5350841-A Amide derivatives of gangliocides including aminoacids or amino sulfonic acids for nervous system disorders FIDIA S.P.A. (IT) 1994-09-27 US claimed
EP-0599908-A1 NEW GANGLIOSIDE DERIVATIVES. FIDIA SPA (IT) 1994-06-08 EP claimed
US-5311841-A Administration of medicaments of poultry THAXTON, J. PAUL 1994-05-17 US claimed
WO-1994001147-A2 ADMINISTRATION OF MEDICAMENTS TO POULTRY SANOFI ANIMAL HEALTH, INC. (US) 1994-01-20 WO claimed
WO-1993003049-A1 NEW GANGLIOSIDE DERIVATIVES FIDIA S.P.A. (IT) 1993-02-18 WO claimed
EP-0378318-A1 Process for synthesis of FK-506 and tricarbonyl intermediates MERCK & CO. INC. (US) 1990-07-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540403-B2 Stable composition for catalytic deposition of silver SOD1, CA3, CA1 LMNA 3532/4885KDM4E 2063/4885THRB 1784/4885
US-12546788-B2 Methods for differentiating destructive thyroiditis from other pathological conditions TPO, TSHR, TH LMNA 4267/4885KDM4E 3836/4885THRB 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.