Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.64 |
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | HTR2B | P41595 | 3/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.53 |
| ▸ | TUBB | P07437 | 3/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424861 | 0.84 | HTR2A (0.69) | AOC3HTR2AHTR2BHTR2CTUBB4A | |
| SCHEMBL11225360 | 0.81 | HTR2A (0.60) | AOC3HTR2AHTR2BHTR2CTUBB4A | |
| SCHEMBL4464142 | 0.80 | HTR2A (0.75) | AOC3HTR2AHTR2BHTR2CTUBB4A | |
| SCHEMBL5568951 | 0.79 | PTGS2 (0.63) | AOC3HTR2AHTR2BHTR2CTUBB4A | |
| SCHEMBL8311988 | 0.78 | AOC3 (1.00) | AOC3HTR2AHTR2BHTR2CTUBB4A | |
| SCHEMBL16295765 | 0.77 | HTR2A (0.78) | AOC3HTR2AHTR2BHTR2CTUBB4A | |
| SCHEMBL2007007 | 0.77 | TNKS2 (0.68) | AOC3HTR2AHTR2BHTR2CTUBB4A | |
| SCHEMBL900845 | 0.77 | HTR2A (0.60) | AOC3HTR2AHTR2BHTR2CTUBB4A | |
| SCHEMBL9799524 | 0.77 | HTR2A (0.60) | AOC3HTR2AHTR2BHTR2CTUBB4A | |
| SCHEMBL6780613 | 0.77 | HTR2A (0.60) | AOC3HTR2AHTR2BHTR2CTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358938-A | 2,5-Diaryl tetrahydrofurans, tetrahydrothiophenes, 1,3-cyclo-pentanes and pyrrolidines | CYTOMED, INC. (US) | 1994-10-25 | — | — | US | disclosed |