Sugi Predict

Sugi Predict / Compounds / Iodide

Iodide

Iodide

SCHEMBL9306747

CCCCCCCCCCCCCCCCOc1ccc(CN(Cc2cc[n+](C)cc2)C(=O)c2ccccc2OC)c(C)c1.[I-]

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.41
▸ THRA P10827 1/20 0.40
▸ THRB P10828 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL9305994 0.92 THRA (0.40) MAPTTHRATHRBKDM4E
Iodide SCHEMBL9309467 0.92 THRA (0.39) THRATHRBKDM4E
Iodide SCHEMBL9306953 0.89 MAPT (0.43) MAPTTHRATHRB
Iodide SCHEMBL9306486 0.88 POLB (0.44) MAPT
Iodide SCHEMBL9306815 0.87 — —
Iodide SCHEMBL9305526 0.87 KDM4E (0.38) MAPTTHRATHRBKDM4E
Iodide SCHEMBL9305481 0.84 THRA (0.39) THRATHRBKDM4E
Iodide SCHEMBL9307763 0.84 THRA (0.43) THRATHRB
Iodide SCHEMBL9306347 0.83 LMNA (0.44) MAPTTHRATHRB
Iodide SCHEMBL9307428 0.81 MAPT (0.41) MAPTTHRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5328921-A Antagonist of platelet activating factor AMERICAN CYANAMID COMPANY (US) 1994-07-12 — — US disclosed