SCHEMBL9306880

SCHEMBL9306880

N#Cc1ccc2oc(C(CC(=O)S)C(=O)O)nc2c1

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CETP P11597 18/20 0.44
HDAC6 Q9UBN7 1/20 0.40
CEPT1 Q9Y6K0 1/20 0.39
PTGES O14684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9306895 0.81 CETP (0.41) CETPHDAC6CEPT1PTGES
SCHEMBL8973137 0.81 RAB9A (0.43) HDAC6
SCHEMBL8972660 0.81 SMN1; SMN2 (0.47)
SCHEMBL8972426 0.81 LMNA (0.46) CETP
SCHEMBL9305334 0.79 RAB9A (0.42) HDAC6
SCHEMBL9306885 0.79 CETP (0.39) CETPHDAC6CEPT1
SCHEMBL9305580 0.78 ALDH1A1 (0.42) HDAC6
SCHEMBL10892259 0.78 RAB9A (0.50) HDAC6CEPT1
SCHEMBL8972322 0.77 RAB9A (0.43) HDAC6
SCHEMBL15481024 0.77 CETP (0.47) CETPHDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5347008-A Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents CIBA-GEIGY CORPORATION (US) 1994-09-13 US disclosed
US-5152929-A Corrosion inhibitors for water systems CIBA-GEIGY CORPORATION (US) 1992-10-06 US disclosed
US-4612049-A BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID CIBA-GEIGY CORPORATION (US) 1986-09-16 US disclosed