Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10891396 | 0.76 | PRKCZ (0.40) | SHMT2POLBALDH1A1KDM4EAPOBEC3G | |
| SCHEMBL9305093 | 0.75 | MAPT (0.42) | POLBALDH1A1GAANPSR1CYP2C9 | |
| SCHEMBL9305733 | 0.74 | PPARA (0.43) | POLBALDH1A1KDM4EAPOBEC3GTDP1 | |
| SCHEMBL9305788 | 0.73 | HSD17B10 (0.39) | SHMT2POLBALDH1A1GAAKDM4E | |
| SCHEMBL9304461 | 0.72 | POLB (0.36) | POLBALDH1A1KDM4EAPOBEC3GTDP1 | |
| SCHEMBL8973084 | 0.71 | SOAT1 (0.37) | — | |
| SCHEMBL8972664 | 0.71 | SMN1; SMN2 (0.47) | POLBALDH1A1GAAKDM4ETDP1 | |
| SCHEMBL9306232 | 0.71 | DAGLA (0.41) | SHMT2POLBALDH1A1KDM4EAPOBEC3G | |
| SCHEMBL10890658 | 0.71 | LMNA (0.31) | POLB | |
| SCHEMBL9304109 | 0.71 | RAB9A (0.34) | SHMT2POLBALDH1A1KDM4EAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |