Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.45 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18076338 | 0.89 | TPSAB1 (0.47) | CTRB1ALDH1A1ABCB1L3MBTL1ITGB3 | |
| SCHEMBL10688515 | 0.89 | CTRB1 (0.43) | CTRB1ALDH1A1ABCB1MAPK1L3MBTL1 | |
| SCHEMBL11512196 | 0.89 | CTRB1 (0.43) | CTRB1ALDH1A1ABCB1MAPK1L3MBTL1 | |
| SCHEMBL7738508 | 0.88 | TSHR (0.53) | CTRB1ALDH1A1ABCB1MAPK1L3MBTL1 | |
| SCHEMBL22804079 | 0.87 | ALDH1A1 (0.46) | CTRB1ALDH1A1ABCB1ITGB3ITGA2B | |
| SCHEMBL22804098 | 0.87 | ALDH1A1 (0.46) | CTRB1ALDH1A1ABCB1ITGB3ITGA2B | |
| SCHEMBL28790921 | 0.87 | SLC15A1 (0.50) | CTRB1ALDH1A1ABCB1KMT2ACYP1A2 | |
| SCHEMBL5181819 | 0.87 | ALDH1A1 (0.47) | CTRB1ALDH1A1ABCB1MAPK1L3MBTL1 | |
| SCHEMBL28210626 | 0.86 | CTRB1 (0.51) | CTRB1ALDH1A1ABCB1MAPK1L3MBTL1 | |
| SCHEMBL28210627 | 0.86 | CTRB1 (0.51) | CTRB1ALDH1A1ABCB1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364850-A | Analgesics | G. D. SEARLE & CO. (US) | 1994-11-15 | — | — | US | disclosed |
| US-5272175-A | Substituted tyrosyl diamide compounds | G. D. SEARLE & CO. (US) | 1993-12-21 | — | — | US | disclosed |