Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL327647 | 0.84 | TSHR (0.50) | TSHRESR1ALDH1A1MEN1KMT2A | |
| SCHEMBL10326109 | 0.82 | TSHR (0.46) | TSHRESR1ALDH5A1ABATOPRM1 | |
| SCHEMBL7575874 | 0.79 | ALDH1A1 (0.47) | TSHRESR1CA2ESR2ALDH1A1 | |
| SCHEMBL10457933 | 0.79 | ALDH1A1 (0.45) | TSHRALDH1A1MEN1KMT2AGFER | |
| SCHEMBL28637636 | 0.77 | TSHR (0.70) | TSHRESR1ESR2ALDH1A1MEN1 | |
| SCHEMBL28622502 | 0.77 | TP53 (0.49) | TSHRESR1ESR2MEN1KMT2A | |
| SCHEMBL3395276 | 0.74 | TSHR (0.43) | TSHRESR1ESR2KDM4E | |
| SCHEMBL3282238 | 0.74 | CA2 (0.41) | ESR1CA2ESR2ALDH1A1 | |
| SCHEMBL1018958 | 0.72 | ESR1 (0.45) | ESR1CA2ALDH5A1ABATOPRM1 | |
| SCHEMBL11876205 | 0.72 | KMT2A (0.48) | ALDH1A1MEN1KMT2ACYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5362615-A | Stabilizer | AGFA AG (DE) | 1994-11-08 | — | — | US | disclosed |