SCHEMBL327647

SCHEMBL327647

C=CCN(C(N)=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
ALDH1A1 P00352 2/20 0.44
GLA P06280 1/20 0.44
POLB P06746 1/20 0.44
ESR1 P03372 1/20 0.43
HTT P42858 2/20 0.42
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
KDM4E B2RXH2 2/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
ADRA2C P18825 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL946547 0.85 TSHR (0.53) TSHRMEN1KMT2AALDH1A1GLA
SCHEMBL10619595 0.85 ALDH1A1 (0.57) TSHRMEN1KMT2AALDH1A1GLA
SCHEMBL9307563 0.84 TSHR (0.42) TSHRMEN1KMT2AALDH1A1POLB
SCHEMBL5932535 0.83 TSHR (0.51) TSHRMEN1KMT2AALDH1A1GLA
SCHEMBL7504930 0.82 TSHR (0.48) TSHRMEN1KMT2AALDH1A1GLA
SCHEMBL27893727 0.82 TSHR (0.48) TSHRMEN1KMT2AALDH1A1GLA
SCHEMBL10347920 0.82 ALDH1A1 (0.46) TSHRMEN1KMT2AALDH1A1GLA
SCHEMBL3465939 0.82 TP53 (0.45) TSHRMEN1KMT2AALDH1A1GLA
SCHEMBL8035000 0.81 TSHR (0.50) TSHRMEN1KMT2AALDH1A1GLA
SCHEMBL5933100 0.81 TSHR (0.50) TSHRMEN1KMT2AALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344633-A Preparation method of copper-free composite resin brake pad 浙江万赛汽车零部件股份有限公司 2024-07-16 CN claimed
CN-115627002-B Epoxy prepreg formula and preparation method and application thereof 台州市黄岩区武汉理工高性能复合材料技术研究院 2024-02-13 CN claimed
CN-115627002-A Formula, preparation method and application of epoxy prepreg 台州市黄岩区武汉理工高性能复合材料技术研究院 2023-01-20 CN claimed
CN-107108537-B Partial stream distillation 巴斯夫欧洲公司 2020-04-17 CN claimed
US-20090163480-A1 Modified amino acids, pharmaceuticals containing these compounds and method for their production DR. KARL THOMAE GMBH (DE) 2009-06-25 US claimed
US-20040214819-A1 Modified amino acids, pharmaceuticals containing these compounds and method for their production DR. KARL THOMAE GMBH (DE) 2004-10-28 US claimed
US-20030069231-A1 Modified aminoacids, pharmaceuticals containing these compounds and method for their production RUDOLF KLAUS (DE) 2003-04-10 US claimed
US-20010036946-A1 Modified amino acids, pharmaceuticals containing these compounds and method for their production RUDOLF KLAUS (DE) 2001-11-01 US claimed
US-5015762-A Alkoxy substituted ureas as herbicides BASF AKTIENGESELLSCHAFT (DE) 1991-05-14 US claimed
US-4025624-A Phenylalkylamines and phenylalkylureas in combinations to suppress gastric bleeding in aspirin therapy A. H. ROBINS COMPANY, INCORPORATED (US) 1977-05-24 US claimed
CN-118344633-A Preparation method of copper-free composite resin brake pad 浙江万赛汽车零部件股份有限公司 2024-07-16 CN disclosed
CN-115627002-B Epoxy prepreg formula and preparation method and application thereof 台州市黄岩区武汉理工高性能复合材料技术研究院 2024-02-13 CN disclosed
CN-115627002-A Formula, preparation method and application of epoxy prepreg 台州市黄岩区武汉理工高性能复合材料技术研究院 2023-01-20 CN disclosed
CN-109071475-B Method for preparing propylene oxide 巴斯夫欧洲公司 2022-12-27 CN disclosed
CN-107108537-B Partial stream distillation 巴斯夫欧洲公司 2020-04-17 CN disclosed
US-5442060-A Treating hyperlipemia, atherosclerosis MITSUBISHI KASEI CORPORATION (JP) 1995-08-15 US disclosed
EP-0591830-A1 Carboxamide and urea derivatives having ACAT-inhibiting activityM Mitsubishi Chemical Corporation (JP) 1994-04-13 EP disclosed
US-4025624-A Phenylalkylamines and phenylalkylureas in combinations to suppress gastric bleeding in aspirin therapy A. H. ROBINS COMPANY, INCORPORATED (US) 1977-05-24 US disclosed
US-4025624-A Phenylalkylamines and phenylalkylureas in combinations to suppress gastric bleeding in aspirin therapy A. H. ROBINS COMPANY, INCORPORATED (US) 1977-05-24 US disclosed
US-4025624-A Phenylalkylamines and phenylalkylureas in combinations to suppress gastric bleeding in aspirin therapy A. H. ROBINS COMPANY, INCORPORATED (US) 1977-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090163480-A1 Modified amino acids, pharmaceuticals containing these compounds and method for their production PTMS, CHRM1, SRMS TSHR 181/4885MEN1 596/4885KMT2A 2685/4885
US-20040214819-A1 Modified amino acids, pharmaceuticals containing these compounds and method for their production PTMS, SRMS, OPRM1 TSHR 304/4885MEN1 790/4885KMT2A 2655/4885
US-20030069231-A1 Modified aminoacids, pharmaceuticals containing these compounds and method for their production SLC1A5, NEFM, SRMS TSHR 342/4885MEN1 984/4885KMT2A 2610/4885
US-20010036946-A1 Modified amino acids, pharmaceuticals containing these compounds and method for their production PTMS, SRMS, OPRM1 TSHR 304/4885MEN1 790/4885KMT2A 2655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.