Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 1.00 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | KDM5A | P29375 | 2/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308624 | 1.00 | ALOX5 (1.00) | ALOX5SLC1A3SLC1A2SLC1A1EPHX1 | |
| SCHEMBL9308307 | 0.98 | ALOX5 (1.00) | ALOX5SLC1A3SLC1A2SLC1A1EPHX1 | |
| SCHEMBL9308267 | 0.93 | ALOX5 (1.00) | ALOX5SLC1A3SLC1A2SLC1A1EPHX1 | |
| SCHEMBL7760755 | 0.80 | ALOX5 (0.67) | ALOX5EPHX1CYP2D6 | |
| SCHEMBL3567122 | 0.77 | ALOX5 (0.62) | ALOX5EPHX1CYP2D6 | |
| SCHEMBL9306400 | 0.71 | ALOX5 (0.55) | ALOX5EPHX1KDM5APHF8KDM2A | |
| SCHEMBL21939800 | 0.71 | ALOX5 (0.55) | ALOX5EPHX1KDM5APHF8KDM2A | |
| SCHEMBL31553556 | 0.71 | ALOX5 (0.54) | ALOX5EPHX1 | |
| SCHEMBL3124936 | 0.70 | ALOX5 (0.53) | ALOX5EPHX1KDM5APHF8KDM2A | |
| SCHEMBL19448791 | 0.70 | ALOX5 (0.53) | ALOX5KDM5APHF8KDM2AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326787-A | Cycloalkyl N-hydroxy derivatives having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1994-07-05 | — | — | US | disclosed |