Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 1.00 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 3/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307728 | 0.98 | ALOX5 (1.00) | ALOX5SLC1A3SLC1A2SLC1A1EPHX1 | |
| SCHEMBL9308624 | 0.98 | ALOX5 (1.00) | ALOX5SLC1A3SLC1A2SLC1A1EPHX1 | |
| SCHEMBL9308267 | 0.95 | ALOX5 (1.00) | ALOX5SLC1A3SLC1A2SLC1A1EPHX1 | |
| SCHEMBL7760755 | 0.77 | ALOX5 (0.67) | ALOX5EPHX1 | |
| SCHEMBL3567122 | 0.74 | ALOX5 (0.62) | ALOX5EPHX1 | |
| SCHEMBL29629110 | 0.71 | ALOX5 (0.61) | ALOX5SLC1A3SLC1A2SLC1A1EPHX1 | |
| SCHEMBL19448790 | 0.69 | ALOX5 (0.52) | ALOX5KDM5APHF8KDM2AKDM4C | |
| SCHEMBL21939800 | 0.69 | ALOX5 (0.55) | ALOX5EPHX1KDM5APHF8KDM2A | |
| SCHEMBL3115065 | 0.69 | ALOX5 (0.52) | ALOX5EPHX1KDM5APHF8KDM2A | |
| SCHEMBL4429615 | 0.68 | ALOX5 (0.52) | ALOX5SLC1A3SLC1A2SLC1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326787-A | Cycloalkyl N-hydroxy derivatives having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1994-07-05 | — | — | US | disclosed |