Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 3/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21574018 | 0.84 | HTR2C (0.42) | ALOX5EPHX1CTSKCTSSGAA | |
| SCHEMBL8911411 | 0.84 | HTR2C (0.42) | ALOX5EPHX1CTSKCTSSGAA | |
| SCHEMBL7329124 | 0.83 | ALOX5 (0.43) | ALOX5EPHX1CTSKCTSSGAA | |
| SCHEMBL4780561 | 0.81 | ALOX5 (0.39) | ALOX5EPHX1CTSKCTSSGAA | |
| SCHEMBL7186502 | 0.80 | ALOX5 (0.41) | ALOX5EPHX1CTSKCTSSGAA | |
| SCHEMBL6680983 | 0.79 | CTSK (0.37) | ALOX5EPHX1CTSKCTSSGAA | |
| SCHEMBL7702211 | 0.79 | EPHX1 (0.38) | ALOX5EPHX1CTSKCTSSGAA | |
| SCHEMBL1845039 | 0.79 | SSTR4 (0.38) | ALOX5EPHX1CTSKCTSSGAA | |
| SCHEMBL16070291 | 0.79 | ALOX5 (0.37) | ALOX5EPHX1CTSKCTSSGAA | |
| SCHEMBL1843886 | 0.79 | EPHX1 (0.38) | ALOX5EPHX1CTSKCTSSGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326787-A | Cycloalkyl N-hydroxy derivatives having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1994-07-05 | — | — | US | disclosed |