Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 7/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23873637 | 0.85 | ALDH1A1 (0.72) | ALDH1A1LTA4HCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL855997 | 0.84 | CACNA1B (0.58) | LTA4HTP53MAPTGAAFAAH | |
| SCHEMBL2908596 | 0.79 | ALDH1A1 (0.69) | ALDH1A1LTA4HCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9309140 | 0.78 | CACNA1B (0.58) | LTA4HTP53MAPTGAAFAAH | |
| SCHEMBL6394149 | 0.77 | CACNA1B (0.50) | ALDH1A1CYP3A4SMN1; SMN2NPC1LMNA | |
| SCHEMBL10556321 | 0.76 | LTA4H (0.57) | ALDH1A1LTA4HCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13766317 | 0.76 | ALDH1A1 (0.73) | ALDH1A1LTA4HCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9164953 | 0.76 | NR5A1 (0.51) | ALDH1A1CYP3A4SMN1; SMN2NPC1LMNA | |
| SCHEMBL4888697 | 0.76 | CHRNB2 (0.62) | LTA4HTSHRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9367178 | 0.76 | CHRNB2 (0.62) | LTA4HTSHRCYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5208247-A | Antianaphylactic agents or septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0530444-A1 | Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |