Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 8/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013229 | 0.87 | GABRA1 (0.52) | GABRA1GABRB2CNR2MEN1GAA | |
| SCHEMBL323547 | 0.85 | XDH (0.54) | GABRA1GABRB2CNR2MEN1GAA | |
| SCHEMBL6009677 | 0.85 | GABRA1 (0.47) | GABRA1GABRB2CNR2MEN1GAA | |
| Hydrogen Sulfide SCHEMBL6721312 | 0.83 | XDH (0.52) | GABRA1GABRB2CNR2MEN1GAA | |
| SCHEMBL1354945 | 0.78 | GABRA1 (0.48) | GABRA1GABRB2CNR2MEN1GAA | |
| SCHEMBL11037594 | 0.76 | GABRA1 (0.58) | GABRA1GABRB2CNR2MEN1GAA | |
| SCHEMBL45432 | 0.75 | GABRA1 (0.53) | GABRA1GABRB2CNR2MEN1GAA | |
| SCHEMBL28274016 | 0.75 | SRD5A1 (0.46) | GABRA1GABRB2CNR2MEN1GAA | |
| SCHEMBL28947809 | 0.74 | AKR1B1 (0.45) | GABRA1GABRB2CNR2MEN1GAA | |
| SCHEMBL10454553 | 0.74 | GABRA1 (0.62) | GABRA1GABRB2CNR2MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344980-A | Process for the preparation of 1,3,5-tris(4'-hydroxyaryl)benzene | HOECHST CELANESE CORP. (US) | 1994-09-06 | — | — | US | disclosed |
| US-5300698-A | Process for the prepartion of 1,3,5-tris(4'-hydroxyaryl)benzene | HOECHST CELANESE CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| WO-1993014053-A1 | PROCESS FOR THE PREPARATION OF 1,3,5-TRIS(4'-HYDROXYARYL)BENZENE | HOECHST CELANESE CORPORATION (US) | 1993-07-22 | — | — | WO | disclosed |
| WO-1993014065-A1 | PROCESS FOR PREPARING 1,3,5- TRIS(4'-HYDROXYPHENYL)BENZENE AND ITS DERIVATIVES | HOECHST CELANESE CORPORATION (US) | 1993-07-22 | — | — | WO | disclosed |