Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.32 |
| ▸ | CES1 | P23141 | 7/20 | 0.31 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634989 | 0.84 | AKR1B1 (0.39) | CES1CES2MEN1KMT2AHSD17B10 | |
| SCHEMBL9336189 | 0.83 | GPR84 (0.41) | FAAHMEN1CYP1A2KMT2AHSD17B10 | |
| SCHEMBL3467327 | 0.83 | GPR84 (0.41) | FAAHMEN1CYP1A2KMT2AHSD17B10 | |
| Methacrylic Acid SCHEMBL7696921 | 0.81 | FNTA (0.37) | MEN1KMT2AHSD17B10 | |
| SCHEMBL158481 | 0.80 | APEX1 (0.36) | CES1CES2MEN1KMT2AHSD17B10 | |
| SCHEMBL8230756 | 0.74 | GRIK1 (0.33) | CES1CES2 | |
| Styrene SCHEMBL3968403 | 0.72 | LMNA (0.43) | CES1CES2MEN1KMT2A | |
| SCHEMBL8139925 | 0.72 | CAMK2A (0.34) | — | |
| SCHEMBL1133777 | 0.70 | ALDH1A1 (0.40) | CES1 | |
| SCHEMBL8734090 | 0.69 | GRIK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294401-A | Blood gas exchange | TERUMO KABUSHIKI KAISHA (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0354959-B1 | MEMBRANE TYPE ARTIFICIAL LUNG AND PRODUCTION THEREOF | TERUMO KABUSHIKI KAISHA (JP) | 1993-01-20 | — | — | EP | disclosed |
| EP-0354959-A1 | MEMBRANE TYPE ARTIFICIAL LUNG AND PRODUCTION THEREOF | TERUMO KABUSHIKI KAISHA (JP) | 1990-02-21 | — | — | EP | disclosed |