Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 9/20 | 0.36 |
| ▸ | CLK1 | P49759 | 2/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11882020 | 0.81 | EGFR (0.37) | LMNAEGFRPIK3CDPIK3CA | |
| SCHEMBL346255 | 0.77 | LMNA (0.65) | LMNAEGFRPIK3CDPIK3CAKDM4E | |
| SCHEMBL17917476 | 0.76 | IMPDH2 (0.44) | LMNAEGFRCLK1CDK5CDK5R1 | |
| SCHEMBL30432091 | 0.76 | EGFR (0.47) | LMNAEGFRCLK1PIK3CDPIK3CA | |
| SCHEMBL1096307 | 0.76 | EGFR (0.47) | LMNAEGFRCLK1PIK3CDPIK3CA | |
| SCHEMBL1900105 | 0.75 | LMNA (0.67) | PKMLMNAKDM4EALDH1A1HTT | |
| SCHEMBL18099782 | 0.74 | IMPDH2 (0.43) | PKMLMNACLK1CDK5CDK5R1 | |
| SCHEMBL18839312 | 0.74 | LMNA (0.38) | LMNACLK1CDK5CDK5R1KDM4E | |
| SCHEMBL22045599 | 0.74 | PKM (0.46) | PKMLMNACLK1KDM4EHTT | |
| SCHEMBL25850566 | 0.72 | EGFR (0.48) | LMNAEGFRCLK1PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340808-A | Fused pyridazinoquinazolone derivatives as neurotrophic agents | WARNER LAMBERT COMPANY (US) | 1994-08-23 | — | — | US | disclosed |