Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MMP13 | P45452 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | GCK | P35557 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | FURIN | P09958 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309014 | 0.90 | SRC (0.50) | HTTTDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| Phosphoric Acid SCHEMBL5518515 | 0.88 | HTT (0.61) | HTTSMN1; SMN2MMP13MEN1KMT2A | |
| SCHEMBL83816 | 0.88 | TDP1 (0.61) | HTTTDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27418397 | 0.86 | HTT (0.50) | HTTTDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15085780 | 0.84 | SMN1; SMN2 (0.60) | HTTTDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| Pyrophosphoric Acid SCHEMBL27568703 | 0.82 | HTT (0.47) | HTTTDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10036476 | 0.82 | ALDH1A1 (0.71) | HTTTDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14280533 | 0.82 | HTT (0.56) | HTTTDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15760407 | 0.81 | SRD5A2 (0.58) | HTTTDP1L3MBTL1ALDH1A1MMP13 | |
| SCHEMBL11511401 | 0.81 | HTT (0.58) | HTTSMN1; SMN2MMP13MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278212-A | Hydroxy phenyl organo phosphorus compound | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-01-11 | — | — | US | disclosed |