Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GCK | P35557 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PNLIP | P16233 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27395625 | 0.88 | ALDH1A1 (0.50) | HTTL3MBTL1TDP1ALDH1A1HSD17B1 | |
| SCHEMBL10849592 | 0.86 | CA2 (0.56) | L3MBTL1TDP1ALDH1A1TSHRNPC1 | |
| Phosphoric Acid SCHEMBL9308118 | 0.86 | HTT (0.56) | HTTL3MBTL1TDP1ALDH1A1HSD17B1 | |
| SCHEMBL27396334 | 0.83 | ALDH1A1 (0.57) | HTTL3MBTL1TDP1ALDH1A1HSD17B1 | |
| SCHEMBL27395622 | 0.82 | TSHR (0.56) | HTTL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL27430217 | 0.80 | MEN1 (0.47) | HTTL3MBTL1TDP1SMN1; SMN2LMNA | |
| SCHEMBL9309014 | 0.80 | SRC (0.50) | HTTL3MBTL1TDP1ALDH1A1HSD17B1 | |
| Phosphoric Acid SCHEMBL5518515 | 0.78 | HTT (0.61) | HTTMMP13SMN1; SMN2PNLIPFFAR1 | |
| SCHEMBL83816 | 0.78 | TDP1 (0.61) | HTTL3MBTL1TDP1ALDH1A1GFER | |
| SCHEMBL27418971 | 0.78 | GCK (0.45) | L3MBTL1ALDH1A1SMN1; SMN2GCKFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1089614-A | Alpha-phosphonosulfonate squalene synthetase inhibitors and method | SQUIBB & SONS INC (US) | 1994-07-20 | — | — | CN | disclosed |