Sugi Predict

Sugi Predict / Compounds / Iodide

Iodide

Iodide

SCHEMBL9308526

CCCCCCCCCCCCCCOc1c(CN(Cc2cc[n+](C)cc2)C(=O)c2ccccc2OC)cccc1C(C)(C)C.[I-]

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.41
▸ BCHE P06276 2/20 0.38
▸ HDAC1 Q13547 1/20 0.38
▸ HDAC6 Q9UBN7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL9304874 0.92 BCHE (0.39) MAPTBCHE
Iodide SCHEMBL9307713 0.89 TP53 (0.42) MAPT
Iodide SCHEMBL9307525 0.85 MAPT (0.39) MAPT
Iodide SCHEMBL9306025 0.85 THRA (0.42) —
Iodide SCHEMBL9306925 0.84 BCHE (0.44) MAPTBCHE
Iodide SCHEMBL9307106 0.81 MAPT (0.40) MAPTBCHEHDAC6
Iodide SCHEMBL9307210 0.80 LMNA (0.37) —
Iodide SCHEMBL9306347 0.80 LMNA (0.44) MAPT
Iodide SCHEMBL9306256 0.80 TP53 (0.46) MAPT
Iodide SCHEMBL9306747 0.80 MAPT (0.41) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5328921-A Antagonist of platelet activating factor AMERICAN CYANAMID COMPANY (US) 1994-07-12 — — US disclosed