Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307698 | 0.89 | ALOX5 (0.50) | MAOBMRGPRX4RAB9A | |
| SCHEMBL8306162 | 0.79 | MEN1 (0.79) | KMT2AMEN1MAOBNR4A2NR4A1 | |
| SCHEMBL7809050 | 0.77 | KMT2A (0.57) | KMT2AMEN1MAOBNR4A2ALDH1A1 | |
| SCHEMBL16115550 | 0.77 | KMT2A (0.60) | KMT2AMEN1MAOBNR4A2NR4A1 | |
| SCHEMBL8953741 | 0.76 | KMT2A (0.50) | KMT2AMEN1MAOBNR4A2ALDH1A1 | |
| SCHEMBL9257608 | 0.76 | KMT2A (0.44) | KMT2AMEN1MAOBNR4A2HIF1A | |
| SCHEMBL16137686 | 0.76 | KMT2A (0.59) | KMT2AMEN1MAOBNR4A2ALDH1A1 | |
| SCHEMBL9310392 | 0.75 | FFAR1 (0.39) | KMT2AMEN1MAOBHIF1AFFAR1 | |
| SCHEMBL5042093 | 0.72 | ALOX5 (0.55) | KMT2AMEN1MAOBALDH1A1HIF1A | |
| SCHEMBL31160636 | 0.72 | MEN1 (0.59) | KMT2AMEN1MAOBALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354865-A | Enzyme inhibitor and inhibiting the leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |
| WO-1994005281-A1 | PHENYLMETHYL DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1994-03-17 | — | — | WO | disclosed |